Price: $278.95  

You need a serious pack to handle serious trips. The Osprey Waypoint 85 Backpack gives you enough room to carry absolutely anything you need for your months away from home. When you head to the airport, this pack splits into two bags, so you can check the heavy stuff and carry on what you need for the flight. Use the daypack for hiking around town, and stash the big bag in your hotel room. Unlike other travel bags, this pack includes the plush suspension and well-vented design that you expect from Osprey.